Exciting event produced two safety cars, a 10 laps from home after the incident and Jaime Alguersuari in his Toro Rosso and Renault Vitaly Petrov.
At this stage, the three leaders Vettel Ferrari and McLaren's Fernando Alonso, Jenson Button, were separated by seconds after the side by side, a row that the procedure for seven rounds.
However, with the ambulance to attend Alguersuari and Petrov, he heard was removed, the race had to be a red flag with six laps to go.
The remaining cars will be doubled again in the network, how the mechanics were allowed to attend them, including putting new tires.
Restart behind the safety car for a ride, he left five others and not surprisingly, Vettel managed to push Alonso and Button.
German 23 years now has a phenomenal advantage of 58 points over McLaren's Lewis Hamilton was involved in two incidents and safety car twice came under investigation by the stewards.
Normally, when the sun shines over the duchy, a race that has generally been following the procession.
But that was not the case here.
Fortunately, the pre-race fears of super-soft new Pirelli tires that have been here permanently for the first time a handful of laps is not satisfied.
If it did, it could lead to even more chaos in the case where there was enough effort to create a thriller.
The beginning was fairly routine, except for seven-time world champion and five-time winner Michael Schumacher Monaco lost five seats, fell from fifth to tenth, when he was out of the toes at the first corner Ste Devote.
The 42-year-old immediately regained a place in Hamilton send round inside the Loews hairpin, but only for a formidable movement audacity Briton on lap 10 at Ste Devote to regain ninth.
Both men were experiencing a lot of drama that unfolded as Schumacher retired later, stopping in the middle of the floor of the Rascasse.
This time, it was legitimate, his Mercedes stalled, not as was the case in 2006 when he pretended to an incident in qualifying to try to take the initiative.
As for Hamilton, just before the premature departure of Michael Schumacher on lap 34, the British had tried to shoot inside of Felipe Massa in his Ferrari around the Loews hairpin, as they fought for eighth place .
Unlike his ex-wife daring it not to pay dividends in the form of bits of both cars were disconnected.
Hamilton is still not enough because the car is clearly one of some concern, the British went through a tunnel in Brazil.
Adding insult to injury, Massa went wide at the balls which are then sucked him in a hazard, its new car in full sun with a mangled left.
He brought the safety car in the game for the first time, even before Schumacher had stopped and was pushed down the pit straight withdraw from the flights.
In this phase, all drivers, including Hamilton, running 11 instead, was shot and Rubens Barrichello 67 seconds off the leading trio in fourth was in a dominant position in the front.
When two of these 11 pitted, and left nine on the same round, accumulating behind the safety car, which is facing after a handful of laps.
Hamilton's bid for the podium was sabotaged, however, the guards gave him a drive-through penalty for causing a collision with Massa.
In subsequent rounds, with the button that uses a plan with three stops against two judgments of Alonso and Vettel for one remarkably, the trio got together 16 laps from home.
It became a battle line was on the cards, including Vettel was the tires that have been modified to meet the 16.
Ten laps to have come to turn a series of cars fighting for the minor instead of behind them, which led to the accident Alguersuari, who ran behind Hamilton, and Petrov.
Even after the resumption, after a delay of 21 minutes, Williams was on stage as Pastor Maldonado tried to pass Hamilton at Ste Devote, causing the strike in Venezuela and the McLaren turn into a barrier.
This resulted in a second investigation by the Commissioners of Hamilton, who also seek an incident with Kamui Kobayashi, who finished fifth behind Mark Webber of Red Bull, Adrian Sutil and seventh place.
Renault Nick Heidfeld, Rubens Barrichello in his Williams and Toro Rosso, Sebastien Buemi completed the top-10 points scorers.
Paul di Resta was 12 in his Force India after an incident-strewn race of its own, involving a drive-through.
The Red Bull team boss Christian Horner described the victory as Vettel "a driving champion" on the radio.
After spraying champagne on a police officer after the podium ceremony in front of Prince Albert, were asked to describe their feelings, Vettel said: "It's unbelievable.
"The race was fun inside the car.
"The only chance of winning this competition was to stay away, and I had pressure on Fernando and Jenson behind.
"We then took the group who crashed in front of us ran off, and finally we changed tires again.
"I said the place is crazy. Roulette wheels have spun a lot last night and today kept on spinning.
"But I am happy to add my name to the list of winners here."
Button, who had led after the first stop, and opened a gap on Vettel, until the security incident the first car was left with regret.
"It 's been fun for a couple of laps before the safety car came out first, because it looked really good," said Button.
"We decided to stop three, jumping Seb at first, but when the safety car came out for the first time just as bad.
"At the Monaco Grand Prix you can expect the safety car, but no good if you have a three-stop strategy."
Formula 1 Grand Prix of Monaco, Monte Carlo, Monaco
Leading positions after race (78 Laps):
1 Sebastian Vettel (Ger) Red Bull 2hr 09mins 38.373secs
2 Fernando Alonso (Spa) Ferrari 2:09:39.511
3 Jenson Button (Gbr) McLaren 2:09:40.751
4 Mark Webber (Aus) Red Bull 2:10:01.474
5 Kamui Kobayashi (Jpn) Sauber-Ferrari 2:10:05.289
6 Lewis Hamilton (Gbr) McLaren 2:10:05.583
7 Adrian Sutil (Ger) Force India at 1 Lap
8 Nick Heidfeld (Ger) Renault at 1 Lap
9 Rubens Barrichello (Bra) Williams at 1 Lap
10 Sebastien Buemi (Swi) Scuderia Toro Rosso at 1 Lap
11 Nico Rosberg (Ger) Mercedes GP at 2 Laps
12 Paul di Resta (Gbr) Force India at 2 Laps
13 Jarno Trulli (Ita) Lotus F1 at 2 Laps
14 Heikki Kovalainen (Fin) Lotus F1 at 2 Laps
15 Jerome d'Ambrosio (Bel) Virgin Racing at 3 Laps
16 Vitantonio Liuzzi (Ita) HRT-F1 at 3 Laps
17 Narain Karthikeyan (Ind) HRT-F1 at 4 Laps
18 Pastor Maldonado (Ven) Williams at 5 Laps
19 Vitaly Petrov (Rus) Renault 67 laps completed
20 Jaime Alguersuari (Spa) Scuderia Toro Rosso 66 laps completed
21 Felipe Massa (Bra) Ferrari 32 laps completed,
22 Michael Schumacher (Ger) Mercedes GP 32 laps completed
23 Timo Glock (Ger) Virgin Racing 30 laps completed
24 Sergio Perez (Mex) Sauber-Ferrari Did not start